Professor and Group Leader in the MRC Human Genetics Unit, part of the University of Edinburgh Institute of Genetics and Molecular Medicine, Malcolm has held the Chair of Coloproctology at Edinburgh University and served as Academic Head of the Colorectal Surgery Unit, Western General Hospital in Edinburgh since 2000. He has an active grant portfolio and a strong laboratory research programme focused around the ultimate aim of reducing mortality from large bowel cancer through early detection and prevention. He has focused his research on unravelling the genetic architecture of colorectal cancer risk and defining its functional consequences. His team and his collaborators have been highly successful in identifying genes and genetic risk factors predisposing to colorectal cancer. The ultimate aim is to understand disease causation and apply genetic information to prevention. He has held Cancer Research UK and MRC Programmatic funding for over 20 years, and he is a Group Leader in the MRC Human Genetics Unit as well as a PI in the Edinburgh Cancer Research Centre. His research has been published in over 200 papers, which together have attracted over 24,000 citations from scientists and others working in the field. Malcolm currently sits on various expert review and advisory committees, including the Experimental Medicine Expert Review Panel for Cancer Research UK, MRC Non-Clinical Fellowships Committee, IBD Specialist Advisory Board of the BSG and the Association of Coloproctcology of GB & I. He was awarded the Chancellor’s Award from Edinburgh University and his work was recently acknowledged by the Scottish Cancer Foundation Prize and the award of the Evans Forrest Medal. His NHS clinical practice comprises a substantial caseload of cancer and inflammatory bowel disease.
Scottish Cancer Foundation Lecture